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Apr 12, 2021 · The BTB domain of BCL6 (BCL6BTB) forms a homodimer that mediates transcriptional repression by recruiting its co-repressor proteins to form ...
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Apr 22, 2021 · The BTB domain of BCL6 (BCL6BTB) forms a homodimer that mediates transcriptional repression by recruiting its corepressor proteins to form a ...
Apr 12, 2021 · The BTB domain of BCL6 (BCL6BTB) forms a homodimer that mediates transcriptional repression by recruiting its corepressor proteins to form a ...
Some of the more notable genes that are repressed by BCL6 include the B lymphocyte-induced maturation protein (blimp-1), a transcriptional repressor of c-myc ...
Feb 13, 2014 · BCL6 is a BTB-zinc finger family transcription repressor and a master regulator of the GC response. ... BCL6 protein is highly upregulated in GC B ...
Oct 22, 2019 · These interactions enable BCL6 to repress transcription via the recruitment of co-repressor complexes, which allow for the suppression of more ...
we predict that targeting BCL6 transcriptional repression complexes in malignant B-cells ... B-cell ... The BTB domain has autonomous repression activity and binds.
Mar 3, 2022 · B cell lymphoma 6 (BCL6) is a transcriptional repressor ... BTB Domain ... transcriptional repression and forms a complex with the BCL6-BTB/POZ ...
Mar 18, 2014 · These functions are mediated through the transcriptional repressor activity of Bcl6, and numerous genes have been found to be directly or ...
Aug 15, 2013 · Collec- tively, these data support the notion that BCL6 can repress enhancer elements. Figure 3. Potent BCL6 Repression Occurs within Repressed.